Press Release Distribution

Members Login  |  Register  |  Why Join?   Follow us on Google+Follow us on TwitterFind us on LinkedInFind Us on FacebookSubscribe to our RSS FeedsSubscribe to our YouTube ChannelFind us on RebelMouse

Video Releases    |    Pricing & Distribution Plans    |    Today's News    |    News By Category    |    News By Date    |    Business Directory
All Press Releases for January 15, 2014 »
RSS Feeds RSS Feed     Print this news Printer Friendly     Email this news Email It    Create PDF PDF Version   

Bryan Roth to Speak About Functional Selectivity at GPCR Conference, May 22-23, 2014, Cambridge, MA

Bryan Roth to Speak at GPCR Conference, May 22-23, 2014 in Cambridge, MA
x-small text small text medium text large text

    CAMBRIDGE, MA, January 15, 2014 /24-7PressRelease/ -- Bryan Roth, Professor at UNC Chapel Hill Medical School, will speak about "Structural Insights into GPCR Functional Selectivity" at the GPCR Structure, Function and Drug Discovery Conference, to be held May 22-23, 2014 in Cambridge, MA.

G-protein coupled receptors (GPCRs) represent the single largest target class for therapeutic drug discovery. Recent findings from many labs suggest that drugs which selectively and differentially engage various GPCR down-stream pathways might have unique therapeutic utility. This process is described as functional selectivity and drugs which have this feature are considered to have signaling bias.

Professor Roth will describe recent high resolution GPCR structures that have provided novel insights into the structural requirements responsible for GPCR functional selectivity. For instance, GPCRs exist in a multitude of conformations; these conformations can be selectively engaged by down-stream effectors, including G-proteins and b-arrestins. Dr. Roth will also describe how this information can be utilized for the rational design and testing of biased agonists.

Dr. Roth is a Michael Hooker Distinguished Professor of Pharmacology, Chemical Biology and Medicinal Chemistry at the University of North Carolina Chapel Hill Medical School. He also serves as the director of the NIMH Psychoactive Drug Screening Program. Dr. Roth has published more than 350 papers and has given more than 250 invited talks, mainly in the area of GPCR structure, function and pharmacology.

For more information about the conference, please visit

Press release service and press release distribution provided by

# # #

Read more Press Releases from Kristen Starkey:

Contact Information:
Kristen Starkey

Monrovia, CA
Voice: (626) 256-6405
E-Mail: Email us Here
Website: Visit Our Website
If you have any questions regarding information in this press release, please contact the person listed in the contact module of this page. Please do not attempt to contact 24-7PressRelease. We are unable to assist you with any information regarding this release. 24-7PressRelease disclaims any content contained in this press release. Please see our complete Terms of Service disclaimer for more information.