HOUSTON, TX, November 08, 2013 /24-7PressRelease/
-- The Journal of American Medical Association relayed that testosterone treatment may increase the risk of cardiovascular ailments. The basis of the study cautioned that men with pre-existing cardiovascular ailments might need to avoid testosterone. The holes in this study are so large it is beyond comprehension that any journalist or reporter could take the study seriously.
It's been long understood that untreated prolonged low testosterone can increase the risk of cardiovascular incidence. Although prescribed testosterone, the men in this study remained at a low level state. Nearly half were never retested during treatment. Recent data shows that men with total testosterone below 550 ng/dl increase their risk of cardiovascular incidence, while men 550 ng/dl and above reduce their risk by 30%. Most participants in this study held their testosterone levels at 332 ng/dl.
Since recommended guidelines of treatment were not followed, there were no reports showing measurements of estradiol or hematocrit. High levels of estradiol or hematocrit can increase cardiovascular risk. However, both estradiol and hematocrit are easily managed when proper treatment guidelines are followed.
The study also showed the majority of participants used testosterone patches. Once a popular method of testosterone delivery, testosterone patches are no longer used when proper treatment guidelines are followed. Patches are highly inefficient in terms of optimizing testosterone, resulting in continued hypogonadal symptoms and increased cardiovascular risk.
Perhaps the most startling piece of the study that was missed altogether or largely ignored by most reports was the rate of reported cardiovascular events. Of those taking testosterone, 10% experienced a cardiovascular event. Of those not taking testosterone, 21% experienced a cardiovascular event. The rate of mortality was greater in those who did not take testosterone.
Studies of this nature are difficult to take seriously when their parameters do not meet standard treatment guidelines. Such studies might parallel this absurd example: Shooting a man who was given testosterone, then blaming the testosterone rather than the gaping bullet hole for his demise.
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